snR84

ALTERNATE NAMES: RUF1

LENGTH: 550 nts

PROCESS: Pseudouridine formation in rRNA

TARGET SITE(S):
25S rRNA: Y2266

Guide Domains
  Click number to see the target site in the 2D structure: 25S-2266
Click number to see the approximate location of the modification site in the ribosome: 25S-2266

GENOMIC ORGANIZATION: Independent gene
 

SGD ORF MAP
ORFmap

GENE DISRUPTION PHENOTYPE: Viable

CORRESPONDENCES IN HUMANS AND PLANTS:
Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.

None reported in plants

PHYLOGENETIC CONSERVATION IN FUNGI:
Click here to examine conservation of the snoRNA in fungal genomes using BLAST.

RNA SEQUENCE:

   1 auugcacaac uuaaguuugu cgaggaucau uuuuuugaac ugaaucaugc ucuuuuuaag
  61 ugcuuugaaa cccucgauga augugucaau gugcaaagau aaaccauugu ucucuguuga
 121 ucagugacuu aauguuugcu uuggagaaug auauuuuccc uuuccuauau uugacuuuug
 181 uucuaaaagu uauuuggaga gaaaaggcau gauugagguu gcgacuuuuu cguuuuugcu
 241 uuugcaugga uaauucaucc augcacaucu cacuuuauug gaccuucaag auugguuucc
 301 cauguaauuu aauuuucucu ccucuacauu uaauauguuc uauauuaauu aauaccaauu
 361 gaguugugcg uacuucauug cagauauuuu accagaccug ucugaguuuu ucguucaagu
 421 uugguugaaa ucggcuugag guauaugaac gugguuggga uauggagauu gggagaucaa
 481 agaagcgaaa auaccugaga caguuuuuuu aaaaaagaag cuaaggaaca ugacucaaag
 541 agacacauua

 

YEAST GENOME DATABASE ENTRY:
Click here to view the SGD entry for this snoRNA.

REFERENCES:
McCutcheon, J. P., and S. R. Eddy. 2003. Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res. 31:4119-4128.
Schattner, P., W. A. Decatur, C. A. Davis, M. Ares, Jr., M. J. Fournier, and T. M. Lowe. 2004. Genome-wide searching for pseudouridylation guide snoRNAs: analysis of the Saccharomyces cerevisiae genome. Nucleic Acids Res. 32:4281-4296.
Torchet, C., G. Badis, F. Devaux, G. Costanzo, M. Werner, and A. Jacquier. 2005. The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae. RNA 11:928-938.


Last update: October 13, 2006 7:55 AM.