ALTERNATE NAMES: RUF3
LENGTH: 306 nts
PROCESS: Pseudouridine formation in rRNA
TARGET SITE(S): 18S rRNA: Y1290 18S rRNA: Y1415
GENOMIC ORGANIZATION: Independent gene
GENE DISRUPTION PHENOTYPE: Viable
CORRESPONDENCES IN HUMANS AND PLANTS: Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.
None reported in plants
PHYLOGENETIC CONSERVATION IN FUNGI: Click here to examine conservation of the snoRNA in fungal genomes using BLAST.
RNA SEQUENCE:
1 acccaaaaac aucaagaaaa gccuuucaau aaauugcucu ucucuuggcg aaagaaagcg 61 gggggcaaaa agaaucacgg gacuuauguu ucgggaucuc uuuguuucuu cuuuuuuucc 121 cggagaauaa uuuuuuagga ccaauuaccg uaguugcgac uacaacaauu guuguucaua 181 cccccacgau uuacuuuuug aaaacuaguu uuuggaauaa uaauguugua aaauuucccu 241 uuuuccaccc cgauuuguau uuuauuuuuc guuacaaaau ugggacuaau auuaagggcg 301 acaguu
YEAST GENOME DATABASE ENTRY:Click here to view the SGD entry for this snoRNA.
REFERENCES: McCutcheon, J. P., and S. R. Eddy. 2003. Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res. 31:4119-4128. Schattner, P., W. A. Decatur, C. A. Davis, M. Ares, Jr., M. J. Fournier, and T. M. Lowe. 2004. Genome-wide searching for pseudouridylation guide snoRNAs: analysis of the Saccharomyces cerevisiae genome. Nucleic Acids Res. 32:4281-4296. Torchet, C., G. Badis, F. Devaux, G. Costanzo, M. Werner, and A. Jacquier. 2005. The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae. RNA 11:928-938.
