ALTERNATE NAMES: RUF2
LENGTH: 268 nts
PROCESS: Pseudouridine formation in rRNA
TARGET SITE(S): 25S rRNA: Y1110 25S rRNA: Y2349 25S rRNA: Y2351
GENOMIC ORGANIZATION: Independent gene
GENE DISRUPTION PHENOTYPE: Viable
CORRESPONDENCES IN HUMANS AND PLANTS: Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.
Click here and see that yeast and Arabidopsis have corresponding modifications and guide snoRNAs.
PHYLOGENETIC CONSERVATION IN FUNGI: Click here to examine conservation of the snoRNA in fungal genomes using BLAST.
RNA SEQUENCE:
1 auggcucuuc aacacauuuc aacauguuca aguaauuugu guuaguggau gaccauuuag 61 gggcugcugg ccugguuacc gggaguuuuu cuuggaucca agcuagcuuu uccgucugau 121 uauccuuaag cuucacaaau uacaauuuuu cccacgcauu aagaaauaag cucaagaugc 181 cuaaaauaag uucuaucccg ccuuuuuucg cuaacaauga cugaguauuc ccacagucua 241 uaguuugaua guagaugggc ggaaauuu
YEAST GENOME DATABASE ENTRY:Click here to view the SGD entry for this snoRNA.
REFERENCES: McCutcheon, J. P., and S. R. Eddy. 2003. Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res. 31:4119-4128. Schattner, P., W. A. Decatur, C. A. Davis, M. Ares, Jr., M. J. Fournier, and T. M. Lowe. 2004. Genome-wide searching for pseudouridylation guide snoRNAs: analysis of the Saccharomyces cerevisiae genome. Nucleic Acids Res. 32:4281-4296. Torchet, C., G. Badis, F. Devaux, G. Costanzo, M. Werner, and A. Jacquier. 2005. The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae. RNA 11:928-938.
