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ALTERNATE NAMES: None reported
LENGTH: 255 nts
PROCESS: 2'-O-methylation of rRNA
TARGET SITE(S): 25S rRNA: Am2256
GENOMIC ORGANIZATION: Independent gene
GENE DISRUPTION PHENOTYPE: Viable
CORRESPONDENCES IN HUMANS AND PLANTS: Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.
None reported in plants
PHYLOGENETIC CONSERVATION IN FUNGI: Click here to examine conservation of the snoRNA in fungal genomes using BLAST.
RNA SEQUENCE:
1 uuuaaugaug aagauuuuaa uuuuccguug gucuauuaag aacagaagua cuucaaaacu 61 acuuuuuaag accauccuuu uacaguauuu uuucaauauu guaaaacuuc ucauuuacuu 121 ugugucuuua ugaucucauc guucuggugg accauaauca gacgcacggu auacuucguu 181 ucuguuggag aauauuggga gucuuuuaau gugaugagug gccaacauaa ccuuauaguc 241 auaguuacac ugauu
YEAST GENOME DATABASE ENTRY:Click here to view the SGD entry for this snoRNA.
REFERENCES: Lowe, T. M., and S. R. Eddy. 1999. A computational screen for methylation guide snoRNAs in yeast. Science 283:1168-1171.