ALTERNATE NAMES: Z13
LENGTH: 92 nts
PROCESS: 2'-O-methylation of rRNA
TARGET SITE(S): 18S rRNA: Am420 25S rRNA: Um2921
GENOMIC ORGANIZATION: Independent gene
GENE DISRUPTION PHENOTYPE: Viable
CORRESPONDENCES IN HUMANS AND PLANTS: None reported
PHYLOGENETIC CONSERVATION IN FUNGI: Click here to examine conservation of the snoRNA in fungal genomes using BLAST.
RNA SEQUENCE:
1 uacuaugaug aaugacauua gcgugaacaa ucucugauac aaaaucgaaa gauuuuagga 61 uuagaaaaac uuauguugcc uuccuucuga aa
YEAST GENOME DATABASE ENTRY:Click here to view the SGD entry for this snoRNA.
REFERENCES: Bonnerot, C., L. Pintard, and G. Lutfalla. 2003. Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol. Cell 12:1309-1315. Harismendy, O., C. G. Gendrel, P. Soularue, X. Gidrol, A. Sentenac, M. Werner, and O. Lefebvre. 2003. Genome-wide location of yeast RNA polymerase III transcription machinery. EMBO J. 22:4738-4747. Lapeyre, B., and S. K. Purushothaman. 2004. Spb1p-directed formation of Gm2922 in the ribosome catalytic center occurs at a late processing stage. Mol. Cell 16:663-669. Lowe, T. M., and S. R. Eddy. 1999. A computational screen for methylation guide snoRNAs in yeast. Science 283:1168-1171. Marck, C., R. Kachouri-Lafond, I. Lafontaine, E. Westhof, B. Dujon, and H. Grosjean. 2006. The RNA polymerase III-dependent family of genes in hemiascomycetes: comparative RNomics, decoding strategies, transcription and evolutionary implications. Nucleic Acids Res. 34:1816-1835. Preti, M., E. Guffanti, E. Valitutto, and G. Dieci. 2006. Assembly into snoRNP controls 5'-end maturation of a box C/D snoRNA in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 351:468-473. Zhou, H., and L. H. Qu. (unpublished).
