snR41

ALTERNATE NAMES: None reported

LENGTH: 110 nts

PROCESS: 2'-O-methylation of rRNA

TARGET SITE(S):
18S rRNA: Am541, Gm1126

Guide Domains
 
Details of the guides at the Lowe Lab S. cerevisiae Methylation Guide snoRNA Database.
  Click number to see the target site in the 2D structure:18S-541, 18S-1126
Click number to see the approximate location of the modification site in the ribosome:18S-541, 18S-1126

GENOMIC ORGANIZATION: Polycistronic gene
 

SGD ORF MAP
ORFmap

GENE DISRUPTION PHENOTYPE: Viable

CORRESPONDENCES IN HUMANS AND PLANTS:
Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.
Click here and see that yeast and Arabidopsis have corresponding modifications and guide snoRNAs.

PHYLOGENETIC CONSERVATION IN FUNGI:
Click here to examine conservation of the snoRNA in fungal genomes using BLAST.

RNA SEQUENCE:

   1 uccccuauga uuaaaaauua uuaaucauau accaauuguu ccgacugaau agugguuuaa
  61 cuacaugucg acaacccuuu uucguuaagu uucagccuug uaugaggggu
 

YEAST GENOME DATABASE ENTRY:
Click here to view the SGD entry for this snoRNA.

REFERENCES:
Bachellerie, J. P., B. Michot, M. Nicoloso, A. Balakin, J. Ni, and M. J. Fournier. 1995. Antisense snoRNAs: a family of nucleolar RNAs with long complementarities to rRNA. Trends Biochem. Sci. 20:261-264.
Ni, J., and M. J. Fournier. (unpublished). In regards to 2'-O-methylation of rRNA.
Lowe, T. M., and S. R. Eddy. 1999. A computational screen for methylation guide snoRNAs in yeast. Science 283:1168-1171.
Kos, M., and D. Tollervey. 2005. The putative RNA helicase Dbp4p is required for release of the U14 snoRNA from preribosomes in Saccharomyces cerevisiae. Mol. Cell 20:53-64.


Last update: October 13, 2006 6:26 AM.