snR191

ALTERNATE NAMES: None reported

LENGTH: 274 nts

PROCESS: Pseudouridine formation in rRNA

TARGET SITE(S):
25S rRNA: Y2258
25S rRNA: Y2260

Guide Domains
  Click number to see the target site in the 2D structure: 25S-2258, 25S-2260
Click number to see the approximate location of the modification site in the ribosome: 25S-2258, 25S-2260

GENOMIC ORGANIZATION: Intronic snoRNA
 

SGD ORF MAP
ORFmap

GENE DISRUPTION PHENOTYPE: Viable

CORRESPONDENCES IN HUMANS AND PLANTS:
Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.

Click here and see that yeast and Arabidopsis have corresponding modifications and guide snoRNAs.

PHYLOGENETIC CONSERVATION IN FUNGI:
Click here to examine conservation of the snoRNA in fungal genomes using BLAST.

RNA SEQUENCE:

  1 uaccaaaccu uuuugucagg gugcuucucu auccguuuua ggauaaacuu aucuacagaa
 61 gugucuguua cuguuuugga agaguaauac uguucgcuua uccauauuuc cccguucugg
121 ggaagccuca uggguaaauu agaaggacaa ccuuuguuuu aaagguauac cuucgcuuuu
181 uagaacagcg aggaucuuau gaguugagcu uuuguuauuu gagacuuuau cucgggcucc
241 auacaauaug uucguaguaa agauccucac aauu

 

YEAST GENOME DATABASE ENTRY:
Click here to view the SGD entry for this snoRNA.

REFERENCES:
Badis, G., M. Fromont-Racine, and A. Jacquier. 2003. A snoRNA that guides the two most conserved pseudouridine modifications within rRNA confers a growth advantage in yeast. RNA 9:771-779.


Last update: October 5, 2006 3:09 PM.