ALTERNATE NAMES: RNA161
LENGTH: 161 nts
PROCESS: Pseudouridine formation in rRNA
TARGET SITE(S): 18S rRNA: Y632 18S rRNA: Y766
GENOMIC ORGANIZATION: Independent gene
GENE DISRUPTION PHENOTYPE: Viable
CORRESPONDENCES IN HUMANS AND PLANTS: Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.
Click here and see that yeast and Arabidopsis have corresponding modifications and guide snoRNAs.
PHYLOGENETIC CONSERVATION IN FUNGI: Click here to examine conservation of the snoRNA in fungal genomes using BLAST.
RNA SEQUENCE:
1 uaaauauaca acacccagua uuuuuggcug cccgugucuu ucucuaccac ggguagucuc 61 ucuaagcugg cagauagaug uuuauugaac cgcuuaaguu ccguugugaa guuuucgucu 121 uucaggcugu auuucauaac acuacuguag uucacacaua c
YEAST GENOME DATABASE ENTRY:Click here to view the SGD entry for this snoRNA.
REFERENCES: Olivas, W. M., D. Muhlrad, and R. Parker. 1997. Analysis of the yeast genome: identification of new non-coding and small ORF-containing RNAs. Nucleic Acids Res. 25:4619-4625. Schattner, P., W. A. Decatur, C. A. Davis, M. Ares, Jr., M. J. Fournier, and T. M. Lowe. 2004. Genome-wide searching for pseudouridylation guide snoRNAs: analysis of the Saccharomyces cerevisiae genome. Nucleic Acids Res. 32:4281-4296. Torchet, C., G. Badis, F. Devaux, G. Costanzo, M. Werner, and A. Jacquier. 2005. The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae. RNA 11:928-938.
