snR76

ALTERNATE NAMES: Z6

LENGTH: 104 nts

PROCESS: 2'-O-methylation of rRNA

TARGET SITE(S):
25S rRNA: Cm2197

Guide Domains
 
Details of the guide at the Lowe Lab S. cerevisiae Methylation Guide snoRNA Database.
  Click number to see the target site in the 2D structure: 25S-2197
Click number to see the approximate location of the modification site in the ribosome:25S-2197

GENOMIC ORGANIZATION: Polycistronic gene
 

SGD ORF MAP
ORFmap

GENE DISRUPTION PHENOTYPE: Viable

CORRESPONDENCES IN HUMANS AND PLANTS:
Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.
 
None reported in plants

PHYLOGENETIC CONSERVATION IN FUNGI:
Click here to examine conservation of the snoRNA in fungal genomes using BLAST.

RNA SEQUENCE:

   1 uggaaaugag gauccacagc acugggcacu gagggggaaa caaauauccu uucaaaugag
  61 ugacaaugcu uuagcgggcc uagaaaaccc gcgcaacuga ucca

YEAST GENOME DATABASE ENTRY:
Click here to view the SGD entry for this snoRNA.

REFERENCES:
Qu, L. H., A. Henras, Y. J. Lu, H. Zhou, W. X. Zhou, Y. Q. Zhu, J. Zhao, Y. Henry, M. Caizergues-Ferrer, and J. P. Bachellerie. 1999. Seven novel methylation guide small nucleolar RNAs are processed from a common polycistronic transcript by Rat1p and RNase III in yeast. Mol. Cell. Biol. 19:1144-1158.
Lowe, T. M., and S. R. Eddy. 1999. A computational screen for methylation guide snoRNAs in yeast. Science 283:1168-1171.


Last update: October 13, 2006 7:41 AM.