E. coli 23S rRNA

   1  GGUUAAGCGA CUAAGCGUAC ACGGUGGAUG CCCUGGCAGU CAGAGGCGAU

  51  GAAGGACGUG CUAAUCUGCG AUAAGCGUCG GUAAGGUGAU AUGAACCGUU

 101  AUAACCGGCG AUUUCCGAAU GGGGAAACCC AGUGUGUUUC GACACACUAU

 151  CAUUAACUGA AUCCAUAGGU UAAUGAGGCG AACCGGGGGA ACUGAAACAU

 201  CUAAGUACCC CGAGGAAAAG AAAUCAACCG AGAUUCCCCC AGUAGCGGCG

 251  AGCGAACGGG GAGCAGCCCA GAGCCUGAAU CAGUGUGUGU GUUAGUGGAA

 301  GCGUCUGGAA AGGCGCGCGA UACAGGGUGA CAGCCCCGUA CACAAAAAUG

 351  CACAUGCUGU GAGCUCGAUG AGUAGGGCGG GACACGUGGU AUCCUGUCUG

 401  AAUAUGGGGG GACCAUCCUC CAAGGCUAAA UACUCCUGAC UGACCGAUAG

 451  UGAACCAGUA CCGUGAGGGA AAGGCGAAAA GAACCCCGGC GAGGGGAGUG

 501  AAAAAGAACC UGAAACCGUG UACGUACAAG CAGUGGGAGC ACGCUUAGGC

 551  GUGUGACUGC GUACCUUUUG UAUAAUGGGU CAGCGACUUA UAUUCUGUAG

 601  CAAGGUUAAC CGAAUAGGGG AGCCGAAGGG AAACCGAGUC UUAACUGGGC

 651  GUUAAGUUGC AGGGUAUAGA CCCGAAACCC GGUGAUCUAG CCAUGGGCAG

 701  GUUGAAGGUU GGGUAACACU AACUGGAGGA CCGAACCGAC UAAUm⁷GΨm⁵UGAA
formation of m¹G745 catalyzed by RrmA Ψ746 catalyzed by RluA formation of m⁵U747 catalyzed by RumB

 751  AAAUUAGCGG AUGACUUGUG GCUGGGGGUG AAAGGCCAAU CAAACCGGGA

 801  GAUAGCUGGU UCUCCCCGAA AGCUAUUUAG GUAGCGCCUC GUGAAUUCAU

 851  CUCCGGGGGU AGAGCACUGU UUCGGCAAGG GGGUCAUCCC GACUUACCAA

 901  CCCGAUGCAA ACUGCGAAUA CCGGAGAAUG UUAUCACGGG AGACACACGG

 951  CGGGΨGCUAA CGUCCGUCGU GAAGAGGGAA ACAACCCAGA CCGCCAGCUA
formation of Ψ955, 2504,2580 catalyzed by RluC

1001  AGGUCCCAAA GUCAUGGUUA AGUGGGAAAC GAUGUGGGAA GGCCCAGACA

1051  GCCAGGAUGU UGGCUUAGAA GCAGCCAUCA UUUAAAGAAA GCGUAAUAGC

1101  UCACUGGUCG AGUCGGCCUG CGCGGAAGAU GUAACGGGGC UAAACCAUGC

1151  ACCGAAGCUG CGGCAGCGAC GCUUAUGCGU UGUUGGGUAG GGGAGCGUUC

1201  UGUAAGCCUG CGAAGGUGUG CUGUGAGGCA UGCUGGAGGU AUCAGAAGUG

1251  CGAAUGCUGA CAUAAGUAAC GAUAAAGCGG GUGAAAAGCC CGCUCGCCGG

1301  AAGACCAAGG GUUCCUGUCC AACGUUAAUC GGGGCAGGGU GAGUCGACCC

1351  CUAAGGCGAG GCCGAAAGGC GUAGUCGAUG GGAAACAGGU UAAUAUUCCU

1401  GUACUUGGUG UUACUGCGAA GGGGGGACGG AGAAGGCUAU GUUGGCCGGG

1451  CGACGGUUGU CCCGGUUUAA GCGUGUAGGC UGGUUUUCCA GGCAAAUCCG

1501  GAAAAUCAAG GCUGAGGCGU GAUGACGAGG CACUACGGUG CUGAAGCAAC

1551  AAAUGCCCUG CUUCCAGGAA AAGCCUCUAA GCAUCAGGUA ACAUCAAAUC

1601  GUACCCCAAA CCGACACm⁶AGG UGGUCAGGUA GAGAAUACCA AGGCGCUUGA
formation of m⁶A1618 catalyzed by RlmF

1651  GAGAACUCGG GUGAAGGAAC UAGGCAAAAU GGUGCCGUAA CUUCGGGAGA

1701  AGGCACGCUG AUAUGUAGGU GAGGUCCCUC GCGGAUGGAG CUGAAAUCAG

1751  UCGAAGAUAC CAGCUGGCUG CAACUGUUUA UUAAAAACAC AGCACUGUGC

1801  AAACACGAAA GUGGACGUAU ACGGUGUGAC GCCUm²GCCCGG UGCCGGAAGG
formation of m²G1835 catalyzed by RlmG

1851  UUAAUUGAUG GGGUUAGCGC AAGCGAAGCU CUUGAUCGAA GCCCCGGUAA

1901  ACGGCGGCCG ΨAACm³ΨAΨAAC GGUCCUAAGG UAGCGAAAm⁵UU CCUUGUCGGG
formation of Ψ1911,1915,1917 catalyzed by RluD Ψ1911,m³1915,1917 pseudouridylated by RluD; m³Ψ1915 methylation is catlyzed by RlmH formation of Ψ1911,1915,1917 catalyzed by RluD formation of m⁵U1939 catalyzed by RumA

1951  UAAGUUCCGA Cm⁵CUGCACGAA UGGCGUAAUG AUGGCCAGGC UGUCUCCACC
formation of m⁵C1962 catalyzed by RlmI

2001  CGAGACUCAG UGAAAUUGAA CUCGCUGUGm⁶A AGAUGCAGUG UACCCGCGGC
m⁶A2030 (enzyme awaits identification)

2051  AAGACGGAAA GACCCCGUm⁷GA ACCUUUACUA UAGCUUGACA CUGAACAUUG
m⁷G2069 (enzyme awaits identification)

2101  AGCCUUGAUG UGUAGGAUAG GUGGGAGGCU UUGAAGUGUG GACGCCAGUC

2151  UGCAUGGAGC CGACCUUGAA AUACCACCCU UUAAUGUUUG AUGUUCUAAC

2201  GUUGACCCGU AAUCCGGGUU GCGGACAGUG UCUGGUGGGU AGUUUGACUG

2251  GmGGCGGUCUC CUCCUAAAGA GUAACGGAGG AGCACGAAGG UUGGCUAAUC
formation of Gm2251 catalyzed by RlmB

2301  CUGGUCGGAC AUCAGGAGGU UAGUGCAAUG GCAUAAGCCA GCUUGACUGC

2351  GAGCGUGACG GCGCGAGCAG GUGCGAAAGC AGGUCAUAGU GAUCCGGUGG

2401  UUCUGAAUGG AAGGGCCAUC GCUCAACGGA UAAAAGGUAC UCCGm²GGGADA
formation of m²G2445 catalyzed by RlmL D2449

2451  ACAGGCΨGAU ACCGCCCAAG AGUUCAUAUC GACGGCGGUG UUUGGCACCmU
formation of Ψ2457 catalyzed by RluE formation of Cm2498 catalyzed by RlmM

2501  CGm²AΨGUCGGC UCAUCACAUC CUGGGGCUGA AGUAGGUCCC AAGGGUAUGG
formation of m²A2503 catalyzed by RlmN formation of Ψ955, 2504,2580 catalyzed by RluC

2551  CUmGUUCGCCA UUUAAAGUGG UACGCGAGCΨ GGGUUUAGAA CGUCGUGAGA
formation of Um2552 catalyzed by RrmJ (RlmE) formation of Ψ955, 2504,2580 catalyzed by RluC

2601  CAGΨΨCGGUC CCUAUCUGCC GUGGGCGCUG GAGAACUGAG GGGGGCUGCU
formation of Ψ2604 catalyzed by RluF formation of Ψ2605 catalyzed by RluB

2651  CCUAGUACGA GAGGACCGGA GUGGACGCAU CACUGGUGUU CGGGUUGUCA

2701  UGCCAAUGGC ACUGCCCGGU AGCUAAAUGC GGAAGAGAUA AGUGCUGAAA

2751  GCAUCUAAGC ACGAAACUUG CCCCGAGAUG AGUUCUCCCU GACCCUUUAA

2801  GGGUCCUGAA GGAACGUUGA AGACGACGAC GUUGAUAGGC CGGGUGUGUA

2851  AGCGCAGCGA UGCGUUGAGC UAACCGGUAC UAAUGAACCG UGAGGCUUAA

2901  CCUU

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