snR74

ALTERNATE NAMES: Z4

LENGTH: 80 nts

PROCESS: 2'-O-methylation of rRNA

TARGET SITE(S):
18S rRNA: Am28

Guide Domains
 
Details of the guide at the Lowe Lab S. cerevisiae Methylation Guide snoRNA Database.
  Click number to see the target site in the 2D structure: 18S-28
Click number to see the approximate location of the modification site in the ribosome:18S-28

GENOMIC ORGANIZATION: Polycistronic gene
 

SGD ORF MAP
ORFmap

GENE DISRUPTION PHENOTYPE: Viable

CORRESPONDENCES IN HUMANS AND PLANTS:
Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.
Click here and see that yeast and Arabidopsis have corresponding modifications and guide snoRNAs.

PHYLOGENETIC CONSERVATION IN FUNGI:
Click here to examine conservation of the snoRNA in fungal genomes using BLAST.

RNA SEQUENCE:

   1 gcagaagaug aaacaaauua cucaaauaga caagcauaug ucugaucuuc augauugaaa
  61 agagcaauua gugucugaug
 

YEAST GENOME DATABASE ENTRY:
Click here to view the SGD entry for this snoRNA.

REFERENCES:
Qu, L. H., A. Henras, Y. J. Lu, H. Zhou, W. X. Zhou, Y. Q. Zhu, J. Zhao, Y. Henry, M. Caizergues-Ferrer, and J. P. Bachellerie. 1999. Seven novel methylation guide small nucleolar RNAs are processed from a common polycistronic transcript by Rat1p and RNase III in yeast. Mol. Cell. Biol. 19:1144-1158.
Lowe, T. M., and S. R. Eddy. 1999. A computational screen for methylation guide snoRNAs in yeast. Science 283:1168-1171.


Last update: October 13, 2006 7:40 AM.