snR39b

ALTERNATE NAMES: None reported

LENGTH: 95 nts

PROCESS: 2'-O-methylation of rRNA

TARGET SITE(S):
25S rRNA: Gm805

Guide Domains
 
Details of the guide at the Lowe Lab S. cerevisiae Methylation Guide snoRNA Database.
  Click number to see the target site in the 2D structure: 25S-805
Click number to see the approximate location of the modification site in the ribosome: 25S-805

GENOMIC ORGANIZATION: Independent gene
 

SGD ORF MAP
ORFmap

GENE DISRUPTION PHENOTYPE: Viable

CORRESPONDENCES IN HUMANS AND PLANTS:
Click here and see that yeast and humans have corresponding modifications and guide snoRNAs.
Click here and see that yeast and Arabidopsis have corresponding modifications and guide snoRNAs.

PHYLOGENETIC CONSERVATION IN FUNGI:
Click here to examine conservation of the snoRNA in fungal genomes using BLAST.

RNA SEQUENCE:

   1 uuuagugaug auacugccga uucuggcauu ccaaaaagug acuagcaaaa uugcgauguu
  61 gucaacuuaa auuacaccau cuuucggggc ugaua

YEAST GENOME DATABASE ENTRY:
Click here to view the SGD entry for this snoRNA.

REFERENCES:
Nicoloso, M., L. H. Qu, B. Michot, and J. P. Bachellerie. 1996. Intron-encoded, antisense small nucleolar RNAs: the characterization of nine novel species points to their direct role as guides for the 2'-O-ribose methylation of rRNAs. J. Mol. Biol. 260:178-195.
Lowe, T. M., and S. R. Eddy. 1999. A computational screen for methylation guide snoRNAs in yeast. Science 283:1168-1171.


Last update: October 13, 2006 6:21 AM.