Publications

Home Research Publications People Lab Links

	Bowden M.G., Heuck A.P., Ponnuraj K., Kolosova E., Choe D., Gurusiddappa S., Narayana S.V.L. , Johnson A.E., and Hook M. 2008 Evidence for the "Dock, Lock and Latch" ligand binding mechanism of the staphylococcal MSCRAMM SdrG. *The Journal of Biological Chemistry, 283, (1), 638-647. [JBC Online]*
	Heuck A.P., Savva C.G., Holzenburg A., Johnson A.E. 2007 Conformational changes that effect oligomerization and initiate pore formation are triggered throughout perfringolysin O upon binding to cholesterol *The Journal of Biological Chemistry, 282(31): 22629-37 [JBC Online]*
	Heuck A.P., Johnson A.E. 2005 Membrane recognition and pore formation by bacterial pore-forming toxins In Protein-lipid interactions, L. Tamm Editor [Wiley-VHC]
	Heuck A.P., Tweten R.K., Johnson A.E. 2003 Assembly and topography of the prepore complex in cholesterol-dependent cytolysins *The Journal of Biological Chemistry, 278(33):31218-25 [Pubmed]*
	Ramachandran R., Heuck A.P., Tweten R.K., Johnson A.E. 2002 Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin *Nature Structural Biology, 9(11):823-7 [PubMed]*
	Hotze E.M., Heuck A.P., Czajkowsky D.M., Shao Z., Johnson A.E., Tweten R.K. 2002 Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin *The Journal of Biological Chemistry, 277(13):11597-605 [PubMed]*
	Heuck A.P., Johnson A.E. 2002 Pore-forming protein structure analysis in membranes using multiple independent fluorescence techniques *Cell Biochemistry and Biophysics, 36(1):89-101 [PubMed]*
	Heuck A.P., Tweten R.K., Johnson A.E. 2001 Beta-barrel pore-forming toxins:intriguing dimorphic proteins *Biochemistry, 40(31):9065-73 [PubMed]*
	Heuck A.P. , Hotze E.M., Tweten R.K., Johnson A.E. 2000 Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes *Molecular Cell, 6(5):1233-42 [PubMed]*
	Shatursky O., Heuck A.P., Shepard L.A., Rossjohn J., Parker M.W., Johnson A.E., Tweten R.K. 1999 The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins *Cell, 99(3):293-9 [PubMed]*
	Shepard L.A., Heuck A.P., Hamman B.D., Rossjohn J., Parker M.W., Ryan K.R., Johnson A.E., Tweten R.K. 1998 Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: an alpha-helical to beta-sheet transition identified by fluorescence spectroscopy *Biochemistry, 37(41):14563-74 [PubMed]*
	Heuck A.P., Wolosiuk R.A. 1997 Fluoresceinthiocarbamyl-insulin: a potential analytical tool for the assay of disulfide bond reduction *Journal of Biochemical and Biophysical Methods, 34(3):213-25 [PubMed]*
	Heuck A.P., Wolosiuk R.A. 1997 Di-fluoresceinthiocarbamyl-insulin: a fluorescent substrate for the assay of protein disulfide oxidoreductase activity *Analytical Biochemistry, 248(1):94-101 PubMed]*